Category U
Muscle & Growth Factors
Myostatin pathway, IGF and tissue-growth factor research.
- Compounds
- 7
- Human data
- 1
This category holds 7 compounds. By evidence level: 1 human data, 5 preclinical, 1 in vitro / limited. The badge describes the published research, not the product. How to read the badges.
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PreclinicalIGF
IGF-1 LR3
IGF-1 analogue
83-amino-acid IGF-1 analogue with an arginine substitution at position 3, giving low IGF-binding protein affinity and high IGF-1 receptor affinity.
- 0.1 mg
- 1 mg
-
PreclinicalIGD
IGF-DES
Truncated IGF-1
Truncated IGF-1 lacking three N-terminal amino acids, which does not bind IGF-binding proteins but retains IGF-1 receptor activity.
- 2 mg
-
PreclinicalFM
MGF
IGF-1Ec splice-variant peptide
Peptide derived from the E domain of the IGF-1Ec splice variant, studied in cell models for myoblast proliferation and differentiation.
- 2 mg
-
LimitedFMP
PEG-MGF
Pegylated MGF
MGF E-domain peptide attached to polyethylene glycol to slow clearance; its biology is inferred from unmodified MGF.
- 2 mg
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PreclinicalFST
Follistatin 344
Myostatin and activin binder
Secreted glycoprotein, here the 344-amino-acid isoform, that binds and neutralises myostatin and activins; studied for muscle mass in animals.
- 1 mg
-
PreclinicalGDF-8
GDF-8
Myostatin (protein)
Growth differentiation factor-8, or myostatin, a TGF-beta family protein made mainly in skeletal muscle that negatively regulates muscle growth.
- 1 mg
-
HumanAE1
ACE-031
ActRIIB-Fc fusion protein
Fusion protein of the activin receptor type IIB extracellular domain and human IgG1 Fc, acting as a soluble decoy for myostatin.
- 1 mg
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