Category V
Mitochondrial & Longevity
Mitochondrial peptides, NAD+ biology, senescence and AMPK or PPAR-delta pathway tools.
- Compounds
- 8
- Blends
- 1
- Human data
- 2
This category holds 8 compounds, including 1 research blend. By evidence level: 2 human data, 6 preclinical. The badge describes the published research, not the product. How to read the badges.
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PreclinicalET
Epitalon
Tetrapeptide (pineal)
Synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for telomerase induction in cultured human fibroblasts, with published work mostly from one group.
- 10 mg
- 50 mg
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PreclinicalF4
FOXO4-DRI
Senolytic peptide
D-retro-inverso peptide designed to disrupt the FOXO4-p53 interaction, studied as a senolytic that triggers apoptosis in senescent cells.
- 2 mg
- 5 mg
- 10 mg
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PreclinicalMS
MOTS-c (Human)
Mitochondrial-derived peptide
Mitochondrial-derived 16-amino-acid peptide from the 12S rRNA gene, studied for folate-cycle inhibition, AMPK activation and muscle metabolism.
- 10 mg
- 15 mg
- 20 mg
- 30 mg
- 40 mg
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Human2S
SS-31
Mitochondria-targeted peptide
Mitochondria-targeted tetrapeptide (elamipretide) interacting with cardiolipin, studied for electron transport and mitochondrial oxidative stress.
- 5 mg
- 10 mg
- 20 mg
- 50 mg
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PreclinicalNJ
NAD+
Redox coenzyme
Redox coenzyme central to cellular energy metabolism and a substrate for sirtuins, PARP enzymes and CD38, studied in ageing biology.
- 100 mg
- 500 mg
- 1000 mg
-
HumanAicar
AICAR
AMPK activator
Cell-permeable adenosine analogue (acadesine) converted to ZMP, an AMP mimic, and used as a research tool to activate AMPK signalling.
- 50 mg
- 100 mg
-
PreclinicalGW
GW-0742
PPAR-delta agonist (small molecule)
Selective small-molecule PPAR-beta/delta agonist, not a peptide, studied for its role in regulating fatty-acid oxidation and energy metabolism.
- 2 mg
- 5 mg
- 10 mg
- 15 mg
- 20 mg
- +6 more
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PreclinicalBlend
NAD+ + MOTS-c + 5-Amino-1MQ
Longevity blend
Research blend of NAD+, MOTS-c and 5-Amino-1MQ, an NNMT inhibitor, with components studied separately in metabolism and ageing research.
- 120 mg
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