Alarelin ALA
GnRH agonist
Synthetic nonapeptide GnRH agonist that desensitises pituitary receptors on continued exposure, studied in endocrinology and fish spawning research.
Evidence level. Published human clinical data exists, from trials or approved use. About the badges
- Class
- GnRH agonist
- Category
- Reproductive & Endocrine
- Type
- Single compound
- Abbreviation
- ALA
- Development and regulatory status
- GnRH agonist drug used in China; not US-approved
What researchers study
Synthetic nonapeptide GnRH agonist. It stimulates the pituitary GnRH receptor and, with continued exposure, desensitises it, lowering gonadotropin and sex-steroid output. It is also used in fish spawning research.
Research areas
- Ovulation and reproductive models
- Endometriosis and uterine leiomyoma research
- Fish spermiation induction studies
- Slow-release microparticle formulation studies
Reported findings
Summaries of published results. Each one is tagged with the type of study behind it. They describe research outcomes and are not claims about any product. Why study type matters.
- case report
A phase I trial participant developed severe acute hepatocellular injury judged highly probable drug-related, which resolved after discontinuation
- fish
In sterlet sturgeon, slow-release alarelin microparticles induced spermiation similar to carp pituitary treatment at 24 and 48 h
Studied alongside
Compounds that appear together in research because their mechanisms complement each other, or as comparators. The reasons given are research reasoning, not recommendations for use.
- Triptorelin Acetateanother GnRH agonist, used as internal standard in alarelin assays
- Gonadorelinnative GnRH counterpart for pituitary-response comparisons
- HCGovulation-induction comparator in reproduction studies
