GHRP-6 Acetate GR6
GHS-R1a agonist
Acetate salt of the hexapeptide GHRP-6, a ghrelin-receptor (GHS-R1a) agonist that stimulates pituitary growth hormone release and food intake.
Evidence level. Published human clinical data exists, from trials or approved use. About the badges
- Class
- GHS-R1a agonist
- Category
- Growth Hormone Axis
- Type
- Single compound
- Abbreviation
- GR6
- Development and regulatory status
- Not approved; investigational research peptide
What researchers study
Acetate salt of the synthetic hexapeptide GHRP-6, a ghrelin-receptor (GHS-R1a) agonist and one of the earliest growth hormone-releasing peptides. It stimulates pituitary GH release and food intake in the studies reviewed.
Research areas
- Ghrelin-receptor, GH release and appetite-pathway studies
- Hypothalamic feeding-circuit activation in mice
- Cardiac and lung injury models in rodents
- Peptide salt-form stability and solubility
Reported findings
Summaries of published results. Each one is tagged with the type of study behind it. They describe research outcomes and are not claims about any product. Why study type matters.
- review
Systemic GHRP-6 is described as stimulating GH release in humans and rats, as background to a 2025 mouse study
- rodent
In mice, GHRP-6 increased food intake through greater meal frequency and size and raised neuronal activation in the hypothalamic arcuate nucleus
- rodent
In mouse lung-injury models induced by LPS or zymosan, GHRP-6 was tested for limiting lung damage and later fibrosis
Studied alongside
Compounds that appear together in research because their mechanisms complement each other, or as comparators. The reasons given are research reasoning, not recommendations for use.
- GHRP-6free-base listing of the same peptide
- GHRP-2 Acetaterelated ghrelin-receptor agonist in acetate form
- CJC-1295 (no DAC)GHRH analogue that synergises with ghrelin-receptor agonists
