DSIP DS
Delta sleep-inducing peptide
Naturally occurring nonapeptide first described as a sleep-promoting factor, studied in sleep, neurotransmitter, circadian and hormonal research.
Evidence level. Published human clinical data exists, from trials or approved use. About the badges
- Class
- Delta sleep-inducing peptide
- Category
- Neuro, Cognitive & Sleep
- Type
- Single compound
- Abbreviation
- DS
- Development and regulatory status
- Not approved; research peptide with limited, mostly older human data
What researchers study
Naturally occurring nonapeptide (molecular weight about 849) first described as a sleep-promoting factor. Reviews report wider effects on electrophysiology, neurotransmitter levels, circadian and hormonal measures; its mechanism remains poorly defined.
Research areas
- Sleep architecture in rabbit and rodent models
- Stress-response and hormonal-signalling studies
- Circadian and locomotor-pattern studies
- Sleep-laboratory studies in insomnia patients
Reported findings
Summaries of published results. Each one is tagged with the type of study behind it. They describe research outcomes and are not claims about any product. Why study type matters.
- review
A 1984 review reported DSIP induced mainly delta sleep in rabbits, rats, mice and humans, with a U-shaped activity curve
- human trial
In a double-blind study of 16 chronic insomnia patients, DSIP gave higher sleep efficiency and shorter latency than placebo, though effects were judged weak
Studied alongside
Compounds that appear together in research because their mechanisms complement each other, or as comparators. The reasons given are research reasoning, not recommendations for use.
