Matrixyl MX10
Palmitoyl pentapeptide
Trade name for palmitoyl pentapeptide-4 (Pal-KTTKS), a fatty-acid-linked synthetic peptide designed as a signalling molecule for skin collagen.
Evidence level. Evidence is mostly cell-based, cosmetic-ingredient data, or otherwise limited. About the badges
- Class
- Palmitoyl pentapeptide
- Category
- Skin, Hair & Cosmetic
- Type
- Single compound
- Abbreviation
- MX10
- Development and regulatory status
- Cosmetic ingredient (palmitoyl pentapeptide-4)
What researchers study
Matrixyl is the trade name for palmitoyl pentapeptide-4 (Pal-KTTKS), a fatty-acid-linked synthetic peptide designed as a signalling molecule to stimulate collagen production in skin.
Research areas
- Collagen synthesis in skin-cell cultures
- Matrikine signal-peptide mechanism studies
- Topical anti-wrinkle formulation testing
- Wound-healing models in rodents
Reported findings
Summaries of published results. Each one is tagged with the type of study behind it. They describe research outcomes and are not claims about any product. Why study type matters.
- human trial
A 12-week double-blind split-face study of 93 women aged 35-55 found significant wrinkle and fine-line reduction versus a placebo moisturiser
- rodent
A 2022 rat study of Matrixyl patch and cream reported 63.5% to 81.8% wound-healing improvement versus sham
Studied alongside
Compounds that appear together in research because their mechanisms complement each other, or as comparators. The reasons given are research reasoning, not recommendations for use.
