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Skin, Hair & Cosmetic

Matrixyl MX10

Palmitoyl pentapeptide

Trade name for palmitoyl pentapeptide-4 (Pal-KTTKS), a fatty-acid-linked synthetic peptide designed as a signalling molecule for skin collagen.

In vitro / limited

Evidence level. Evidence is mostly cell-based, cosmetic-ingredient data, or otherwise limited. About the badges

MATRIXYL10 mgLyophilised PowderFOR RESEARCH USE ONLY
Class
Palmitoyl pentapeptide
Type
Single compound
Abbreviation
MX10
Development and regulatory status
Cosmetic ingredient (palmitoyl pentapeptide-4)

What researchers study

Matrixyl is the trade name for palmitoyl pentapeptide-4 (Pal-KTTKS), a fatty-acid-linked synthetic peptide designed as a signalling molecule to stimulate collagen production in skin.

Research areas

  • Collagen synthesis in skin-cell cultures
  • Matrikine signal-peptide mechanism studies
  • Topical anti-wrinkle formulation testing
  • Wound-healing models in rodents

Reported findings

Summaries of published results. Each one is tagged with the type of study behind it. They describe research outcomes and are not claims about any product. Why study type matters.

  1. human trial

    A 12-week double-blind split-face study of 93 women aged 35-55 found significant wrinkle and fine-line reduction versus a placebo moisturiser

  2. rodent

    A 2022 rat study of Matrixyl patch and cream reported 63.5% to 81.8% wound-healing improvement versus sham

Studied alongside

Compounds that appear together in research because their mechanisms complement each other, or as comparators. The reasons given are research reasoning, not recommendations for use.

  • GHK-CuCopper peptide with overlapping collagen and matrix-remodelling effects in skin models
  • Snap-8Neuromuscular-signalling peptide often studied alongside matrix peptides in cosmetic research

Related profiles

Related compounds

All Skin, Hair & Cosmetic

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