Glutathione GTT
Tripeptide antioxidant
Glutamate-cysteine-glycine tripeptide and main endogenous cellular antioxidant, studied as a cofactor in redox balance and xenobiotic metabolism.
Evidence level. Published human clinical data exists, from trials or approved use. About the badges
- Class
- Tripeptide antioxidant
- Category
- Antioxidants & Specialty
- Type
- Single compound
- Abbreviation
- GTT
- Development and regulatory status
- Endogenous tripeptide; supplement ingredient; injectable form not approved by some regulators
What researchers study
Tripeptide of glutamate, cysteine and glycine and the main endogenous cellular antioxidant. It serves as a cofactor for glutathione peroxidases and glutathione S-transferases in redox balance and in the handling of xenobiotics.
Research areas
- Redox balance and oxidative-stress assays
- Detoxification-pathway enzyme studies
- Blood glutathione-store measurements in human trials
- Immune-cell redox studies
Reported findings
Summaries of published results. Each one is tagged with the type of study behind it. They describe research outcomes and are not claims about any product. Why study type matters.
- human trial
In a randomized, double-blind trial of 54 healthy adults, glutathione supplementation raised glutathione levels in blood, erythrocytes, plasma and lymphocytes, returning to baseline after washout
- human trial
Oxidative-stress markers indicated a reduction in both supplementation groups
Studied alongside
Compounds that appear together in research because their mechanisms complement each other, or as comparators. The reasons given are research reasoning, not recommendations for use.
- AstaxanthinBoth studied in oxidative-stress and redox-balance research
- Vitamin B-12 (large vial)Methylation cycle linked to cysteine supply for glutathione synthesis
- SS-31Mitochondrial oxidative-stress peptide studied alongside antioxidant systems
