Mitochondrial & Longevity Research blend
NAD+ + MOTS-c + 5-Amino-1MQ
Longevity blend
Research blend of NAD+, MOTS-c and 5-Amino-1MQ, an NNMT inhibitor, with components studied separately in metabolism and ageing research.
Evidence level. Evidence comes mainly from animal or other preclinical models. For a blend, the rating covers the combination itself; each component has its own profile. About the badges
- Class
- Longevity blend
- Category
- Mitochondrial & Longevity
- Type
- Research blend
- Development and regulatory status
- Research blend; components not approved drugs; blend itself unstudied
Blend composition
NAD+ 100 mg + MOTS-c 10 mg + 5-Amino-1MQ 10 mg
Each component is profiled separately in the catalogue: NAD+, MOTS-c (Human), 5-Amino-1MQ.
What researchers study
Three-component research blend: NAD+ (redox coenzyme), MOTS-c (mitochondrial-derived peptide linked to AMPK) and 5-Amino-1MQ (small-molecule inhibitor of nicotinamide N-methyltransferase, NNMT). Components are studied separately; no blend-level studies were located.
Research areas
- Combined cellular-energy, mitochondrial and NNMT-pathway studies
- AMPK and NAD+ salvage-pathway cross-talk
- Metabolic models in diet-induced obese mice
Reported findings
Summaries of published results. Each one is tagged with the type of study behind it. They describe research outcomes and are not claims about any product. Why study type matters.
- rodent
5-Amino-1MQ limited body-weight and fat-mass gain, improved glucose tolerance and attenuated hepatic steatosis in diet-induced obese mice
- rodent
MOTS-c treatment prevented diet-induced obesity and insulin resistance in mice
Studied alongside
Compounds that appear together in research because their mechanisms complement each other, or as comparators. The reasons given are research reasoning, not recommendations for use.
- NAD+Component redox coenzyme in energy metabolism
- MOTS-c (Human)Component mitochondrial peptide linked to AMPK activation
- 5-Amino-1MQComponent NNMT inhibitor acting on nicotinamide metabolism
